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Cell line expression
Protein structure
ACTL6B
Actin like 6BACTL6, BAF53B
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Top validated antibodies |
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| antibodies-online |  ABIN2840276 |
3 references | Polyclonal |
WB
IHC
FC
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| LSBio | LS-C830791 |
Polyclonal |
WB
EL
IHC
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| Aviva Systems Biology | OAAB02744 |
Polyclonal |
WB
EL
IHC
FC
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| St John's Laboratory | STJ70537 |
Polyclonal |
EL
IHC
FC
OA
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| NovoPro Bioscience Inc. | 122521 |
Polyclonal |
WB
EL
IHC
FC
|
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