FBXL13

Members of the F-box protein family, such as FBXL13, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). [supplied by OMIM, Mar 2008]

Description

F-box and leucine rich repeat protein 13

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

7 (102813230 - 103074843)

Ensembl ID

ENSG00000161040  (ver. 103.38)

Orthologs

Mouse Fbxl13: ENSMUSG00000048520

UniProt

Q8NEE6

neXtProt

NX_Q8NEE6

Human splice variants
Mouse splice variants

Protein structure