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CRY1
Cryptochrome circadian regulator 1PHLL1
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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| Proteintech Group |  13474-1-AP |
28 references | Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | PA5-13124 |
2 references | Polyclonal |
WB
IHC
OA
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| LSBio | LS-B5393 |
Monoclonal |
WB
EL
ICC
IHC
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| OriGene | AM31168PU-N |
Monoclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | H00001407-M01 |
Monoclonal |
WB
EL
ICC
IHC
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