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Protein structure
GP6
Glycoprotein VI plateletGPVI
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Top validated antibodies |
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| LSBio |  LS-C83910 |
Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN499916 |
4 references | Polyclonal |
WB
EL
IHC
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| Abnova Corporation | PAB13394 |
4 references | Polyclonal |
WB
IHC
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| Boster Biological Technology | A02208 |
Polyclonal |
WB
EL
ICC
IHC
|
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| Biorbyt | orb1238920 |
Polyclonal |
WB
EL
ICC
IHC
|
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