Tissue expression
Cell line expression
Protein structure
CLK2
CDC like kinase 2This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Top validated antibodies |
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Proteintech Group | 11092-1-AP | 3 references | Polyclonal |
WB
EL
IHC
|
|
Atlas Antibodies | HPA055366 | Polyclonal |
WB
ICC
IHC
|
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Biorbyt | orb101417 | Polyclonal |
WB
EL
ICC
IHC |
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Abnova Corporation | PAB29463 | Polyclonal |
WB
ICC
IHC
|
||
antibodies-online | ABIN4299215 | Polyclonal |
WB
ICC
IHC
|
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