Tissue expression
Cell line expression
Protein structure
TLR9
Toll like receptor 9CD289
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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Novus Biologicals | ![]() |
135 references | Monoclonal |
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Acris Antibodies GmbH | ![]() |
34 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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Enzo Life Sciences | ![]() |
13 references | Monoclonal |
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