Tissue expression
Cell line expression
Protein structure
JAK3
Janus kinase 3JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ![]() |
3 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
1 references | Monoclonal |
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Novus Biologicals | ![]() |
1 references | Monoclonal |
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OriGene | ![]() |
Monoclonal |
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GeneTex | ![]() |
Monoclonal |
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