Tissue expression
Cell line expression
Protein structure
ICAM3
Intercellular adhesion molecule 3CD50, CDW50, ICAM-R
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Top validated antibodies |
|||||
OriGene | AM33033PU-N | Monoclonal |
WB
EL
ICC
IP
IHC
FC |
||
Novus Biologicals | NB100-2609 | Monoclonal |
WB
EL
ICC
IP
IHC
FC
RA
|
||
R&D Systems | BBA15 | 1 references | Monoclonal |
WB
EL
ICC
IP
FC
|
|
Invitrogen Antibodies | 17699-1-AP | Polyclonal |
WB
IP
IHC
FC
OA
|
||
LSBio | LS-C338382 | Monoclonal |
WB
ICC
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider