HTATSF1

The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]

Description

HIV-1 Tat specific factor 1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (136497079 - 136512346)

Ensembl ID

ENSG00000102241  (ver. 103.38)

Orthologs

Mouse Htatsf1: ENSMUSG00000067873

UniProt

O43719

neXtProt

NX_O43719

Human splice variants
Mouse splice variants

Protein structure