Tissue expression
Cell line expression
Protein structure
SFRP1
Secreted frizzled related protein 1FRP, FRP-1, SARP2
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
2 references | Polyclonal |
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R&D Systems | ![]() |
6 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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