HOXB13

This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008]

Description

Homeobox B13

Tissue specificity

Group enriched (intestine, prostate)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Transcription factors

Chromosome

17 (48724763 - 48728750)

Ensembl ID

ENSG00000159184  (ver. 103.38)

Orthologs

Mouse Hoxb13: ENSMUSG00000049604

UniProt

Q92826

neXtProt

NX_Q92826

Human splice variants
Mouse splice variants

Protein structure