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Protein structure
IL16
Interleukin 16FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Top validated antibodies |
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| R&D Systems |  AF-316-PB |
2 references | Polyclonal |
WB
ICC
IHC
FC
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| LSBio | LS-C344088 |
Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-20670 |
1 references | Polyclonal |
WB
ICC
IHC
OA
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| Novus Biologicals | AF-316-PB |
2 references | Polyclonal |
WB
ICC
IHC
FC
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| Boster Biological Technology | PB9238 |
1 references | Polyclonal |
WB
EL
ICC
IHC
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