Tissue expression
Cell line expression
Protein structure
CRADD
CASP2 and RIPK1 domain containing adaptor with death domainRAIDD
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Top validated antibodies |
|||||
Invitrogen Antibodies | PA5-80501 | Polyclonal |
WB
EL
ICC
IP
IHC
OA |
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GeneTex | GTX61554 | Monoclonal |
WB
ICC
IP
IHC
FC
|
||
Novus Biologicals | H00008738-M01 | 1 references | Monoclonal |
WB
EL
ICC
|
|
Biorbyt | orb1727615 | Recombinant |
WB
ICC
IP
IHC
FC
|
||
Proteintech Group | 10401-1-AP | Polyclonal |
WB
EL
IP
IHC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider