Tissue expression
Cell line expression
Protein structure
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolaseAICARFT, IMPCHASE, PURH
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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Atlas Antibodies | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Monoclonal |
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Proteintech Group | ![]() |
5 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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GeneTex | ![]() |
Monoclonal |
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