Tissue expression
Cell line expression
Protein structure

SCN1A

Sodium voltage-gated channel alpha subunit 1
FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI 
Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript. [provided by RefSeq, Oct 2015]
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212 antibodies from 31 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Antibodies Incorporated / NeuroMab
2 antibodies
GeneTex
4 antibodies
Invitrogen Antibodies
19 antibodies
Cusabio Biotech Co., Ltd
5 antibodies
Affinity Biosciences
2 antibodies
OriGene
4 antibodies
St John's Laboratory
3 antibodies
antibodies-online
70 antibodies
Acris Antibodies GmbH
2 antibodies
Boster Biological Technology
2 antibodies
Abbkine Scientific Co.Ltd.
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Proteintech Group
1 antibody
Arigo
2 antibodies
Bioworld Technology, Inc
2 antibodies
NSJ Bioreagents
2 antibodies
Creative Biolabs
16 antibodies
MyBioSource
4 antibodies
Abnova Corporation
1 antibody
Atlas Antibodies
1 antibody
Absolute Antibody
14 antibodies
Spring Bioscience
4 antibodies
UC Davis/NIH NeuroMab Facility
2 antibodies
Bioss
1 antibody
Novus Biologicals
1 antibody
EMD Millipore
5 antibodies
Abbexa
5 antibodies
Creative Diagnostics
3 antibodies
MilliporeSigma / Merck KGaA
1 antibody
RayBiotech, Inc.
1 antibody