RLN3

This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is proteolytically processed to generate a heterodimeric mature form consisting A and B chains interlinked by disulfide bonds. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]

Description

Relaxin 3

Tissue specificity

Group enriched (parathyroid gland, testis)

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

19 (14028148 - 14031551)

Ensembl ID

ENSG00000171136  (ver. 103.38)

Orthologs

Mouse Rln3: ENSMUSG00000045232

UniProt

Q8WXF3

neXtProt

NX_Q8WXF3

Human splice variants
Mouse splice variants

Protein structure