OR4C5

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

Description

Olfactory receptor family 4 subfamily C member 5

Tissue specificity

Not detected

Predicted location

Membrane

Protein family

G-protein coupled receptors
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins

Chromosome

11 (48365485 - 48366465)

Ensembl ID

ENSG00000176540  (ver. 103.38)

Orthologs

Mouse Olfr1260: ENSMUSG00000042894

UniProt

Q8NGB2

neXtProt

NX_Q8NGB2

Human splice variants
Mouse splice variants

Protein structure