Tissue expression
Cell line expression
Protein structure
CBS
Cystathionine beta-synthaseHIP4
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Top validated antibodies |
|||||
Novus Biologicals | H00000875-M01 | 48 references | Monoclonal |
WB
EL
ICC
IP
IHC
BN |
|
Abnova Corporation | H00000875-M01 | 32 references | Monoclonal |
WB
EL
IP
IHC |
|
Invitrogen Antibodies | PA5-22273 | 1 references | Polyclonal |
WB
ICC
IP
IHC
OA
|
|
antibodies-online | ABIN560206 | 38 references | Monoclonal |
WB
EL
IP
IHC |
|
LSBio | LS-C669963 | Polyclonal |
WB
EL
ICC
IHC |
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