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Protein structure
SP1
Sp1 transcription factorThe protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-29165 |
8 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
OA
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| Proteintech Group | 21962-1-AP |
101 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| GeneTex | GTX110593 |
2 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
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| Novus Biologicals | NB600-233 |
4 references | Polyclonal |
WB
IP
IHC
ChIP
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| antibodies-online | ABIN954894 |
5 references | Polyclonal |
WB
ICC
IHC
FC
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