Tissue expression
Cell line expression
Protein structure
CRADD
CASP2 and RIPK1 domain containing adaptor with death domainRAIDD
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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Proteintech Group | ![]() |
5 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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GeneTex | ![]() |
Monoclonal |
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Novus Biologicals | ![]() |
1 references | Monoclonal |
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Biorbyt | ![]() |
Recombinant |
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