INS-IGF2

This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. [provided by RefSeq, Jul 2008]

Description

INS-IGF2 readthrough

Tissue specificity

Tissue enriched (pancreas)

Predicted location

Secreted to digestive system

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

11 (2132538 - 2161209)

Ensembl ID

ENSG00000129965  (ver. 103.38)

Orthologs

-

UniProt

F8WCM5

neXtProt

NX_F8WCM5

Human splice variants

Protein structure