CIDEC

This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Description

Cell death inducing DFFA like effector c

Tissue specificity

Group enriched (adipose tissue, breast)

Predicted location

Intracellular

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

3 (9866711 - 9880255)

Ensembl ID

ENSG00000187288  (ver. 103.38)

Orthologs

Mouse Cidec: ENSMUSG00000030278

UniProt

Q96AQ7

neXtProt

NX_Q96AQ7

Human splice variants
Mouse splice variants

Protein structure