SYTL5

The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Description

Synaptotagmin like 5

Tissue specificity

Tissue enhanced (brain, stomach)

Subcell location

Nucleoplasm, Microtubules, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

X (38006553 - 38128819)

Ensembl ID

ENSG00000147041  (ver. 103.38)

Orthologs

Mouse Sytl5: ENSMUSG00000054453

UniProt

Q8TDW5

neXtProt

NX_Q8TDW5

Human splice variants
Mouse splice variants

Protein structure