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Protein structure
RNF14
Ring finger protein 14ARA54, HFB30, TRIAD2
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
Top validated antibodies |
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| antibodies-online |  ABIN393809 |
5 references | Monoclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | 26368-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| Proteintech Group | 26368-1-AP |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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| Novus Biologicals | H00009604-M01 |
Monoclonal |
WB
EL
ICC
BN
|
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| Abnova Corporation | H00009604-M01 |
Monoclonal |
WB
EL
ICC
|
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