CBLN1

This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq, Aug 2008]

Description

Cerebellin 1 precursor

Tissue specificity

Group enriched (brain, testis)

Predicted location

Secreted in brain

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16 (49277917 - 49281838)

Ensembl ID

ENSG00000102924  (ver. 103.38)

Orthologs

Mouse Cbln1: ENSMUSG00000031654

UniProt

P23435

neXtProt

NX_P23435

Human splice variants
Mouse splice variants

Protein structure