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P2RX7
Purinergic receptor P2X 7MGC20089, P2X7
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
Top validated antibodies |
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| Proteintech Group |  11144-1-AP |
11 references | Polyclonal |
EL
ICC
IHC
FC
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| antibodies-online | ABIN5869165 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| GeneTex | GTX16827 |
1 references | Polyclonal |
WB
ICC
IHC
FC
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| Invitrogen Antibodies | PA5-25581 |
2 references | Polyclonal |
WB
IHC
OA
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| Novus Biologicals | NBP1-37775 |
2 references | Polyclonal |
WB
EL
IHC
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