KCNH7

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Description

Potassium voltage-gated channel subfamily H member 7

Tissue specificity

Group enriched (brain, retina)

Predicted location

Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Kim et al 2014)
Voltage-gated ion channels

Chromosome

2 (162371407 - 162838767)

Ensembl ID

ENSG00000184611  (ver. 103.38)

Orthologs

Mouse Kcnh7: ENSMUSG00000059742

UniProt

Q9NS40

neXtProt

NX_Q9NS40

Human splice variants
Mouse splice variants

Protein structure