CACNG1

Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010]

Description

Calcium voltage-gated channel auxiliary subunit gamma 1

Tissue specificity

Group enriched (skeletal muscle, tongue)

Predicted location

Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Transporters

Chromosome

17 (67044554 - 67056797)

Ensembl ID

ENSG00000108878  (ver. 103.38)

Orthologs

Mouse Cacng1: ENSMUSG00000020722

UniProt

Q06432

neXtProt

NX_Q06432

Human splice variants
Mouse splice variants

Protein structure