RASAL2

This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Description

RAS protein activator like 2

Tissue specificity

Tissue enhanced (retina)

Subcell location

Plasma membrane, Focal adhesion sites

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
RAS pathway related proteins

Chromosome

1 (178094104 - 178484147)

Ensembl ID

ENSG00000075391  (ver. 103.38)

Orthologs

Mouse Rasal2: ENSMUSG00000070565

UniProt

Q9UJF2

neXtProt

NX_Q9UJF2

Human splice variants
Mouse splice variants

Protein structure