Antibody data

Product number
NBP2-34616-0.1 mg
Provider
Novus Biologicals
Product name
Mouse Monoclonal Myogenin Antibody
Provider product page
Novus Biologicals - NBP2-34616-0.1 mg
Antibody type
Monoclonal
Description
Protein A purified. Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms tumor.
Reactivity
Human, Mouse, Rat, Feline, Porcine
Host
Mouse
Isotype
IgG
Vial size
0.1 mg
Concentration
1.0 mg/ml
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -