POLR2L

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]

Description

RNA polymerase II, I and III subunit L

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
RNA polymerase related proteins

Chromosome

11 (837356 - 842529)

Ensembl ID

ENSG00000177700  (ver. 103.38)

Orthologs

Mouse Polr2l: ENSMUSG00000038489

UniProt

P62875

neXtProt

NX_P62875

Human splice variants
Mouse splice variants

Protein structure