Tissue expression
Cell line expression
Protein structure
SCNN1A
Sodium channel epithelial 1 subunit alphaENaCalpha, SCNN1
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
Top validated antibodies |
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| Invitrogen Antibodies | 26 references | Polyclonal |
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| Proteintech Group | 15 references | Polyclonal |
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| antibodies-online | 1 references | Polyclonal |
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| Abcepta | Polyclonal |
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| NSJ Bioreagents | Polyclonal |
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