CAPZA3

This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility. [provided by RefSeq, Jul 2008]

Description

Capping actin protein of muscle Z-line subunit alpha 3

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

12 (18738119 - 18739188)

Ensembl ID

ENSG00000177938  (ver. 103.38)

Orthologs

Mouse Capza3: ENSMUSG00000041791

UniProt

Q96KX2

neXtProt

NX_Q96KX2

Human splice variants
Mouse splice variants

Protein structure