ASB13

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants, both protein-coding and not protein-coding, have been described for this gene. [provided by RefSeq, Nov 2010]

Description

Ankyrin repeat and SOCS box containing 13

Tissue specificity

Tissue enhanced (liver)

Subcell location

Nucleoplasm, Golgi apparatus

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

10 (5638867 - 5666595)

Ensembl ID

ENSG00000196372  (ver. 103.38)

Orthologs

Mouse Asb13: ENSMUSG00000033781

UniProt

Q8WXK3

neXtProt

NX_Q8WXK3

Human splice variants
Mouse splice variants

Protein structure