MAGEB6

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]

Description

MAGE family member B6

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular

Protein family

Cancer-related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

X (26192440 - 26195646)

Ensembl ID

ENSG00000176746  (ver. 103.38)

Orthologs

-

UniProt

Q8N7X4

neXtProt

NX_Q8N7X4

Human splice variants

Protein structure