DLGAP4

The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

DLG associated protein 4

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Focal adhesion sites

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

20 (36306336 - 36528637)

Ensembl ID

ENSG00000080845  (ver. 103.38)

Orthologs

Mouse Dlgap4: ENSMUSG00000061689

UniProt

Q9Y2H0

neXtProt

NX_Q9Y2H0

Human splice variants
Mouse splice variants

Protein structure