DHX35

DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The function of this gene product which is a member of this family, has not been determined. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2010]

Description

DEAH-box helicase 35

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nuclear bodies, Centrosome

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

20 (38962299 - 39039723)

Ensembl ID

ENSG00000101452  (ver. 103.38)

Orthologs

Mouse Dhx35: ENSMUSG00000027655

UniProt

Q9H5Z1

neXtProt

NX_Q9H5Z1

Human splice variants
Mouse splice variants

Protein structure