PPP2R5C

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Description

Protein phosphatase 2 regulatory subunit B'gamma

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Golgi apparatus, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14 (101761798 - 101927989)

Ensembl ID

ENSG00000078304  (ver. 103.38)

Orthologs

Mouse Ppp2r5c: ENSMUSG00000017843

UniProt

Q13362

neXtProt

NX_Q13362

Human splice variants
Mouse splice variants

Protein structure