MIIP

This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cell division protein 20 and may be involved in regulating mitotic progression. This protein may function as a tumor suppressor by inhibiting the growth or certain cancers. [provided by RefSeq, Sep 2011]

Description

Migration and invasion inhibitory protein

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (12019466 - 12032045)

Ensembl ID

ENSG00000116691  (ver. 103.38)

Orthologs

Mouse Miip: ENSMUSG00000029022

UniProt

Q5JXC2

neXtProt

NX_Q5JXC2

Human splice variants
Mouse splice variants

Protein structure