SORBS3

This gene encodes an SH3 domain-containing adaptor protein. The presence of SH3 domains play a role in this protein's ability to bind other cytoplasmic molecules and contribute to cystoskeletal organization, cell adhesion and migration, signaling, and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Description

Sorbin and SH3 domain containing 3

Tissue specificity

Low tissue specificity

Subcell location

Focal adhesion sites, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

8 (22544986 - 22575788)

Ensembl ID

ENSG00000120896  (ver. 103.38)

Orthologs

Mouse Sorbs3: ENSMUSG00000022091

UniProt

O60504

neXtProt

NX_O60504

Human splice variants
Mouse splice variants

Protein structure