TRMT2B

This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]

Description

TRNA methyltransferase 2 homolog B

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nuclear bodies

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (101009346 - 101052116)

Ensembl ID

ENSG00000188917  (ver. 103.38)

Orthologs

Mouse Trmt2b: ENSMUSG00000067369

UniProt

Q96GJ1

neXtProt

NX_Q96GJ1

Human splice variants
Mouse splice variants

Protein structure