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Protein structure
INVS
InversinNPHP2
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2012]
Top validated antibodies |
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| Proteintech Group |  10585-1-AP |
5 references | Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | PA5-112583 |
Polyclonal |
WB
EL
ICC
IHC
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| NovoPro Bioscience Inc. | 111814 |
Polyclonal |
WB
EL
ICC
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA011769GA01HU |
Polyclonal |
WB
EL
ICC
IHC
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| Wuhan Fine Biotech Co., Ltd. | FNab04369 |
Polyclonal |
WB
EL
ICC
IHC
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