ALDH1L2

This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2010]

Description

aldehyde dehydrogenase 1 family member L2

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

12:q23.3 (105019784 - 105107643)

Ensembl ID

ENSG00000136010  (ver. 99.38)

Orthologs

Mouse Aldh1l2: ENSMUSG00000020256

UniProt

Q3SY69

neXtProt

NX_Q3SY69

Human splice variants
Mouse splice variants