METAP1D

The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]). [supplied by OMIM, Mar 2008]

Description

Methionyl aminopeptidase type 1D, mitochondrial

Tissue specificity

Low tissue specificity

Subcell location

Vesicles

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

2 (171999943 - 172082430)

Ensembl ID

ENSG00000172878  (ver. 103.38)

Orthologs

Mouse Metap1d: ENSMUSG00000041921

UniProt

Q6UB28

neXtProt

NX_Q6UB28

Human splice variants
Mouse splice variants

Protein structure