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- Antigen structure
- References [2]
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- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- ABS 033-04-02 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- GLP-1 Monoclonal Antibody (4)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- ABS 033-04-02 detects the amidated N-terminus of GLP-1(7-37) and GLP-1(7-36) in human samples. ABS 033-04-02 has been successfully used in ELISA procedures. ABS 033-04-02 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36) amide and shows < 0.2% cross-reactivity with GLP-1(1-37), GLP-1(9-36) amide, glucagon, human GIP and exendin-4. ABS 033-04-02 cross-reacts approximately 1% with human GLP-2. Not recommended for sandwich ELISA applications. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 4
- Vial size
- 400 µL
- Concentration
- 1.06 mg/mL
- Storage
- 4° C, store in dark
Submitted references GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys.
Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Agonist, GLP-1-IgG2σ-Fc.
Lu SC, Chen M, Atangan L, Killion EA, Komorowski R, Cheng Y, Netirojjanakul C, Falsey JR, Stolina M, Dwyer D, Hale C, Stanislaus S, Hager T, Thomas VA, Harrold JM, Lloyd DJ, Véniant MM
Cell reports. Medicine 2021 May 18;2(5):100263
Cell reports. Medicine 2021 May 18;2(5):100263
Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Agonist, GLP-1-IgG2σ-Fc.
Yang Y, Chen F, Wan D, Liu Y, Yang L, Feng H, Cui X, Gao X, Song H
PloS one 2016;11(5):e0156449
PloS one 2016;11(5):e0156449
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Glucagon-Like Peptide 1 in endocrine alpha cells from diabetic mic using a Glucagon-Like Peptide 1 monoclonal antibody (Product # ABS 033-04-02) at a dilution of 1:500.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
