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Protein structure
MTMR3
Myotubularin related protein 3FYVE-DSP1, KIAA0371, ZFYVE10
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-24557 |
Monoclonal |
WB
EL
ICC
OA
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| Abnova Corporation | H00008897-M07 |
Monoclonal |
WB
EL
ICC
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| Novus Biologicals | H00008897-M07-100ug |
Monoclonal |
WB
EL
ICC
|
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| antibodies-online | ABIN522387 |
Monoclonal |
WB
EL
ICC
|
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| Proteintech Group | 21336-1-AP |
Polyclonal |
WB
EL
IHC
|
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