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Cell line expression
Protein structure
CAV1
Caveolin 1CAV
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. [provided by RefSeq, Mar 2010]
Top validated antibodies |
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| Invitrogen Antibodies |  MA3-600 |
8 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| Novus Biologicals | NB100-615 |
22 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| Proteintech Group | 16447-1-AP |
48 references | Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN152046 |
16 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| GeneTex | GTX100205 |
2 references | Polyclonal |
WB
ICC
IP
IHC
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