Tissue expression
Cell line expression
Protein structure
CACNA1D
Calcium voltage-gated channel subunit alpha1 DCACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Top validated antibodies |
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| GeneTex | 1 references | Monoclonal |
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| Novus Biologicals | 1 references | Monoclonal |
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| Invitrogen Antibodies | Polyclonal |
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| LSBio | Monoclonal |
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| antibodies-online | 1 references | Monoclonal |
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