FOXA3

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved. [provided by RefSeq, Jul 2008]

Description

Forkhead box A3

Tissue specificity

Group enriched (intestine, liver, pancreas, stomach)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

19 (45863989 - 45873797)

Ensembl ID

ENSG00000170608  (ver. 103.38)

Orthologs

Mouse Foxa3: ENSMUSG00000040891

UniProt

P55318

neXtProt

NX_P55318

Human splice variants
Mouse splice variants

Protein structure