UGT2B17

This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis. [provided by RefSeq, Apr 2010]

Description

UDP glucuronosyltransferase family 2 member B17

Tissue specificity

Group enriched (intestine, liver)

Predicted location

Membrane

Protein family

Enzymes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (68537184 - 68568527)

Ensembl ID

ENSG00000197888  (ver. 103.38)

Orthologs

-

UniProt

O75795

neXtProt

NX_O75795

Human splice variants

Protein structure